A certain amount of ambitiousness, before it reaches the malignant stage, can also be an engine for progress.

Is it malignant?

Get fuller, sexier, more malignant lips today!

In the age of the Portuguese maritime expeditions, sailors were afflicted with the most diverse illnesses: malignant fevers, diarrhea, and the dreaded and frequent scurvy, resulting from a lack of vitamin C caused by malnutrition.

It was an odious face—crafty, vicious, malignant, with shifty, light-grey eyes and white lashes.

The tumor is malignant.

Here, girt with steel, the foremost in the fight, / fierce Juno stands, the Scaean gates before, / and, mad with fury and malignant spite, / calls up her federate forces from the shore."

Various types of tumors exist, both benign and malignant.

Tom is a malignant narcissist.

There are various types of tumors – some benign and some malignant.