Those were drinking days, and most men drank hard. So very great is the improvement Time has brought about in such habits, that a moderate statement of the quantity of wine and punch which one man would swallow in the course of a night, without any detriment to his reputation as a perfect gentleman, would seem, in these days, a ridiculous exaggeration.

It being a name, I think you can just leave it as it is with no detriment to the translation.

How quickly to my detriment cruel Luck has changed!

Freeganism is a total boycott of an economic system where the profit motive has eclipsed ethical considerations and where massively complex systems of productions ensure that all the products we buy will have detrimental impacts most of which we may never even consider.

If you eat a spoonful of sugar or a small piece of whole wheat bread, it seems that the bread would be less detrimental.

Lack of sleep is detrimental to your health.

Mathematics is not detrimental to the appetite.

The poor educational policy is a detriment to Japan.

The family tried to save money by scrimping on food to the detriment of their own health.

For too long society has placed sole emphasis on children's test results, to the detriment of social discipline.