We pushed ahead despite the obstacles. ✬

Despite our efforts, we failed after all. ✬

Despite searching high and low, Tom couldn't find his wallet. ✬

Despite everything, Tom started to relax. ✬

Despite what's happened, I still like Tom. ✬

Despite repeated warnings, Tom didn't stop doing that. ✬

Tom died despite Mary's help. ✬

Despite the concerns, the weather was magnificent. ✬

Despite language difficulties, we were soon friends. ✬

Tom won the race despite his handicap. ✬