A wife's activities are confined to domestic matters.

Tom is in solitary confinement.

A bad cold confined her to her bed.

The findings hold promise for preventing muscle and bone loss in astronauts on prolonged space trips like Mars missions, as well as people on Earth who are confined to bed or need wheelchairs.

She confined herself to her study and wept to her heart's content.

A storm confined them to the house.

'Or Grecians in these timbers lurk confined, / or 'tis some engine of assault, designed / to breach the walls, and lay our houses bare, / and storm the town. Some mischief lies behind. / Trust not the horse, ye Teucrians. Whatso'er / this means, I fear the Greeks, for all the gifts they bear.'

Confinement can drive you insane.

He's still confined to bed.

Tom spent his birthday in solitary confinement.