His behavior alienated his friends.

In high school, he alienated all his friends with his constant mocking.

Tom alienated Mary.

Christmas is supposed to be a happy time to share with the family. For some people, however, who are alienated from their family, or who have no family, it can be a very unhappy time.

With that attitude, you will alienate all of your potential allies.

He felt alienated from society.

In order to conquer the centre, we'll have to alienate the left wing of the party.

Yanni was attempting to alienate Skura from her friends.

How long have you been alienated from your family?

His coolness has alienated his friends.