She takes a new lover while he is in anguish.

Sami's family waited in anguish.

The newspaper told of the mother's anguish at the death of her son.

I will speak in the anguish of my spirit.

Yanni was in anguish.

A terrible scream—a prolonged yell of horror and anguish burst out of the silence of the moor. That frightful cry turned the blood to ice in my veins.

Meanwhile a mingled murmur through the street / rolls onward – wails of anguish, shrieks of fear –, / and though my father's mansion stood secrete, / embowered in foliage, nearer and more near / peals the dire clang of arms, and loud and clear, / borne on fierce echoes that in tumult blend, / war-shout and wail come thickening on the ear.

Yanni could clearly hear the anguish in Rima's voice.

He hid his anguish with a smile.

He is in anguish over her child.